林美华 研究员 硕士生导师
437ccm必赢国际（武汉） 437ccm必赢国际
湖北省武汉市洪山区鲁磨路388号学海楼421室
电 话：027-67885201
Email：linmh@cug.edu.cn
教育与研究经历
2017-至今， 437ccm必赢国际（武汉）437ccm必赢国际（研究员，硕士生导师）
2015-2017， 马里兰大学帕克分校，博士后 （合作导师：Zhihong Nie）
2010-2015， 中国科学院大学上海应用物理研究所，博士学位（导师：樊春海研究员）
2015/3-2015/9 厦门大学，交流学习 （导师：杨朝勇教授）
2006-2010， 福州大学，化学基地班，学士学位（导师：杨黄浩教授）
学术成果
主要从事DNA纳米结构自组装设计及其在生物传感、生物成像的应用，无机纳米材料合成、组装及在生物中的应用。目前为止，在国内外知名期刊上发表论文10余篇，其中包括Nature Protocols, Advance Materials, Angewandte, Analytical Chemistry等杂志，总引用500余次。
获奖与荣誉
中国科学院优秀博士学位论文（2016）
中科院院长优秀奖（2015）、中国科学院/北京市优秀毕业生 (2015)
博士研究生国家奖学金
承担项目与课题
1. DNA纳米结构探针设计及其在单细胞内双信号检测多种生物分子的应用（中央高校基本科研业务费专项资金）
代表性成果
https://www.researchgate.net/profile/Meihua_Lin
1. Meihua Lin#, Ping Song, Guobao Zhou, Xiaolei Zuo,* Ali Aldalbahi, Xiaoding Lou, Jiye Shi, Chunhai Fan Electrochemical detection of nucleic acids, proteins, small molecules and cells using a DNA nanostructure-based universal biosensing platform. Nature Protocols. 2016, 1244-1263.
2. Meihua Lin#, Hao Pei, Fan Yang, Chunhai Fan,* and Xiaolei Zuo* Applications of Gold Nanoparticles in the Detection and Identification of Infectious Diseases and Biothreats. Advanced Materials. 2013, 25, 3490-3496.
3. Meihua Lin#, Jingjing Wang, Guobao Zhou, Jianbang Wang, Na Wu, Jianxin Lu, Jimin Gao, Xiaoqing Chen, Jiye Shi, Xiaolei Zuo*, and Chunhai Fan* Programmable engineering of biosensing interface with tetrahedral DNA nanostructures for ultrasensitive DNA detection. Angewandte Chemie International Edition. 2015, 54, 2151–2155.(Very Important Paper)
4. Meihua Lin#, Yanli Wen#, Lanying Li, Hao Pei, Gang Liu, Haiyun Song, Xiaolei Zuo,Chunhai Fan, and Qing Huang*Target-Responsive, DNA Nanostructure- Based E‑DNA Sensor for microRNA Analysis. Analytical Chemistry. 2014, 86, 2285−2288.
5. Zhilei Ge#, Meihua Lin#, Ping Wang, Hao Pei, Juan Yan, Jiye Shi, Qing Huang, Dannong He, Chunhai Fan, and Xiaolei Zuo* Hybridization Chain Reaction Amplification of MicroRNA Detection with a Tetrahedral DNA Nanostructure-Based Electrochemical Biosensor. Analytical Chemistry. 2014, 86, 2124−2130. (ESI高被引)
6. Jiaoyun Xia, Meihua Lin, Xiaolei Zuo, Shao Su, Lihua Wang, Wei Huang, chunhai Fan, and Qing Huang* Metal Ion-Mediated Assembly of DNA Nanostructures for Cascade Fluorescence Resonance Energy Transfer-Based Fingerprint Analysis. Analytical Chemistry. 2014, 86, 7084-7087.
7. Guobao Zhou, Meihua Lin, Ping Song, Xiaoqing Chen,* Jie Chao, Lianhui Wang, Qing Huang, Wei Huang, Chunhai Fan, and Xiaolei Zuo* Multivalent Capture and Detection of Cancer Cells with DNA Nanostructured Biosensors and Multibranched Hybridization Chain Reaction Amplifi cation. Analytical Chemistry. 2014, 86, 7843-7848.
8. Alireza Abi, Meihua Lin, Hao Pei, Chunhai Fan,* Elena E. Ferapontova,* and Xiaolei Zuo* Electrochemical Switching with 3D DNA Tetrahedral Nanostructures Self-Assembled at Gold Electrodes. ACS Applied Materials & Interfaces.2014, 6, 8928-8931.
9. Yanli Wen, Hao Pei, Ye Shen, Junjie Xi, Meihua Lin, Na Lu, Xizhong Shen, Jiong Li, and Chunhai Fan* DNA Nanostructure-based Interfacial engineering for PCR-free ultrasensitive electro- chemical analysis of microRNA. SCIENTIFIC REPORTS. 2014, 2, 867-871.
10. Chunhua Lu, Juan Li, Meihua Lin, Yiwei Wang, Huanghao Yang,* Xi Chen, and Guonan Chen Amplified Aptamer-Based Assay through Catalytic Recycling of the Analyte. Angewandte Chemie International Edition. 2010, 49, 8454-8457.
11. Xiaoying Lin, Yi Liu, Meihua Lin, Qian Zhang, Zhihong Nie* Synthesis of circular and triangular gold nanorings with tunable optical properties. Chemical Communications. 2017, 53, 10765 -10767.
